Approximately 700,000 strokes occur
annually in the United States; 50
percent of the 550,000 survivors
experience residual
hemiparesis
affecting one side of the body
and
approximately 165,000 of those
individuals have mobility deficits
requiring assistance with walking
[1-3]In this population, hemiparetic
gait is a major problem that limits
mobility, increases risk of falls, and
imposes higher energy demands for basic
daily activities [4-5]. Gait deviations
due to hemiparesis are well documented,
in terms of both clinical manifestation
and biomechanical analyses [6-7].
Classic models of stroke recovery
indicate that improvements in both
upper- and lower-limb motor function
plateau between 3 and 6 months
poststroke [8]. Recent studies have
challenged this assumption by suggesting
that specific training interventions
that target use of the hemiparetic limbs
can improve motor control and neural
plasticity. The research community now
widely accepts that the central nervous
system comprises inherently plastic
neural networks that are continuously
amenable to reorganization in the
service of functional behaviors [9]. As
a consequence, new therapeutic
approaches seek to exploit
experience-based CNS plasticity to
mediate functional improvements. A
common thread among most of these
interventions is an adherence to the
principles of motor learning, as defined
by incorporating high volumes of
task-oriented practice along with the
added dimensions of goal setting and
performance feedback [10].
Studies of therapies that improve
function and induce neuroplasticity in
hemiparetic upper limbs in human
survivors of stroke have supported an
emerging focus on developing new
learning-based strategies for improving
gait and balance function in individuals
with lower-limb hemiparesis after stroke
[11-17]. Here we review evidence that
one particular mode of exercise,
treadmill (TM) training as applied in a
number of approaches, can be employed to
improve gait function in survivors of
stroke with residual hemiparesis. We
will suggest that basic motor learning
strategies can alter underlying neural
mechanisms to improve hemiparetic
function of the lower limb and may also
be effective in recovery of walking
ability after stroke. Following a brief
overview of the rationale and early
results from studies using TM training
with stroke, we provide examples that
illustrate the role of the CNS in
lower-limb motor control and gait. Our
focus then shifts to an overview of how
the neurophysiologyof lower-limb motor
control is sensitive to short-term
adaptations and rapid plasticity.
Finally, we review the early evidence of
central neuroplasticity underlying
lower-limb function and gait using
long-term TM training protocols.
RATIONALE FOR TREADMILL
LOCOMOTOR
LEARNING AFTER STROKE
Findings from spinalized animal models
demonstrate that walking without
supraspinal inputs can occur when the
animal is placed on a moving TM [18].
Thus, several investigations have
studied TM training as a means to
improve locomotor function in subjects
with incomplete
spinal cord injury and stroke.
Visintin et al. first adapted the
findings from spinalized animals to
human experiments, reasoning that
activation of
subcortical neural
structures by TM walking could provide a
physiological stimulus for recovery of
gait function [19-20]. These studies
support the rationale that TM-generated
stepping patterns in neurologically
injured humans can help deliver
repetitive sensory inputs to the spinal
cord, which in turn could mediate
locomotor learning and neural plasticity
through a process of sensory motor
integration [21]. Additional feasibility
for this idea was shown in a study of
the immediate effects of the TM stimulus
on hemiparetic gait patterns in naive
subjects with chronic stroke [22]. While
controlling for walking speed,
paretic
paretic /pa·ret·ic/
(pah-ret´ik)
pertaining to or affected with paresis.
limb stance-swing parameters and
loading impulse immediately became more
symmetrical on the TM compared with
usual
overground
TREADMILL-BASED EXERCISE TRAINING
IMPROVES GAIT FUNCTION
The initial studies with human SCI and
subacute stroke subjects used TM
training in conjunction with partial
body-weight suspension (PBWS
PBWS Performance Based Work Statement
(contracting
mechanism) ). In a
randomized study of more severely
impaired subjects with subacute stroke,
Barbeau and Visintin found TM with PBWS
to be more effective than TM without
PBWS for improving selected mobility
outcomes in those subjects with more
severe motor deficits (i.e., <0.2 m/s
walking velocity and Berg Balance scores
<15) [24]. By week 6 of training, 79
percent of subjects were able to train
at 0 percent PBWS. In a noncontrolled
3-week study, 25 PBWS TM training
sessions improved mobility scores and
gait temporal-distance parameters in
nine nonambulatory stroke subjects [25].
PBWS was not required after day 6 of
training in seven of these nine cases.
Similar results were reported in a
follow-up study using the same approach
in an A-B-A design [26]. These studies
indicate an important role for PBWS as a
bridge to full-weight-bearing TM
exercise, particularly in subjects more
severely affected.
|
HyperMED Clinical Research provides links with all current publications on Hyperbaric Oxygenation, Lokomat (Robotic Gait Assisted Walking) and other break-through we believe relevant to the objective of NeuroRecovery. Clinical Research: Lokomat
Robotic Gait Training in an Adult With Cerebral Palsy: A Case Report Improved treatments and rehabilitation for cerebral palsy (CP) have led to an increased number of children with CP surviving into adulthood. Adults with CP show an increased prevalence of pain, fatigue, and musculoskeletal dysfunction, leading to a decrease in ambulatory function. Recent work has demonstrated the potential benefits of intensive task-specific gait training, including the use of robotic-driven gait orthoses, on motor recovery in children with CP []. In contrast, reports of interventions aimed at improving motor function in adults with CP are lacking. This case study reports on the outcomes of a 6-week intervention of robotic-assisted gait training administered to a 52-year-old woman with right hemiplegia attributable to CP. Improvements were noted in balance, walking speed, and time to negotiate stairs at posttraining and follow-up. Gait analysis showed an increase in step length and a reduction in the period of double support. In conclusion, robotic-assisted gait training may be beneficial in enhancing locomotor function in adults with CP.
Robotic-assisted treadmill therapy improves walking and standing performance in children and adolescents with cerebral palsy. Borggraefe I, Schaefer JS, Klaiber M, Dabrowski E, Ammann-Reiffer C, Knecht B, Berweck S, Heinen F, Meyer-Heim A. Department of Paediatric Neurology and Developmental Medicine, Dr. von Haunersches Children's Hospital, University of Munich, Germany. Eur J Paediatr Neurol. 2010 Feb 5. [Epub ahead of print] Abstract : Task-specific body-weight-supported treadmill therapy improves walking performance in children with central gait impairment. The aim of the study was to investigate the effect of robotic-assisted treadmill therapy on standing and walking performance in children and adolescents with cerebral palsy and to determine parameters influencing outcome. METHODS: 20 Patients (mean age 11.0+/-5.1, 10 males and 10 females) with cerebral palsy underwent 12 sessions of robotic-assisted treadmill therapy using the driven gait orthosis Lokomat. Outcome measures were the dimensions D (standing) and E (walking) of the Gross Motor Function Measure (GMFM). RESULTS: Significant improvements in dimension D by 5.9% (+/-5.2, p=0.001) and dimension E by 5.3% (+/-5.6, p<0.001) of the GMFM were achieved. Improvements in the GMFM D and E were significantly greater in the mildly affected cohort (GMFCS I and II) compared to the more severely affected cohort (GMFCS III and IV). Improvement of the dimension E but not of D correlated positively with the total distance and time walked during the trial (r(s)=0.748, p<0.001). CONCLUSIONS: Children and adolescents with bilateral spastic cerebral palsy showed improvements in the functional tasks of standing and walking after a 3-week trial of robotic-assisted treadmill therapy. The severity of motor impairment affects the amount of the achieved improvement. Copyright © 2010 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved
Ambulatory children with a diagnosis of spastic diplegia due to CP, GMFCS level II to III were enrolled in the study. 21 children aged 6-14 (mean 12.13) with a diagnosis of spastic diplegia due to cerebral palsy (CP) GMFCS level II to III They were randomly allocated to either intervention or control group. were divided into 2 groups. Intervention group (n=12) participated in a 4-week robotic-assisted walking gait training involving max. 3-5 sessions of 45min per week. 20 sessions (45min per session). Transfer of scientific concepts to clinical practice: recent robot-assisted training studies. Waldner A, Tomelleri C, Hesse S. Funct Neurol. 2009 Oct-Dec;24(4):173-7. Abstract: Restoration of motor function is a priority of post-stroke rehabilitation, the aim being to facilitate the patient's reintegration into society. Innovative technologies for neurological rehabilitation must be easy to use and offer patients real benefits, and the treatments they provide must be efficacious and efficient. All these aspects must be carefully evaluated in their development. To achieve restoration of motor function after stroke, task-specific repetitive robot-assisted training of the upper and the lower extremity is currently the most promising approach. The results of clinical trials of robotic devices for upper limb (MIT-Manus, MIME, NeReBot, BiManuTrack, ARMin, ARMOR) and lower limb (LokoHelp, GangTrainer GT1, Haptic Walker, G-EO-Systems, Lokomat) training are here presented with the aim of highlighting the possible gains in motor function due to robotic therapy. Patients who receive robot-assisted training in combination with physiotherapy after stroke are more likely to achieve better motor function than patients trained without these devices, or only with these devices.
Olfactory mucosal autografts and rehabilitation for chronic traumatic spinal cord injury. Participants included paraplegics and well as tetraplegics ranging in age from 19-37 years and with an average of 49 months since the injury. Before surgery, all participants underwent high intensity rehabilitation consisting of range of motion and strengthening exercises, balance training for posture, standing, transfers and gait and pre gait activities for approximately 4 months. The gait activities were either carried out using a Lokomat, which is a robotic-assisted body weight supported treadmill training, or BIONT which is described as assisted over ground walking training. The participants’ own olfactory mucosa was transplanted into the injury site after partial scar removal. There was no control group, with all participants receiving transplants. The intense rehabilitation regimes were continued postoperatively.
Restoration of Walking in Multiple Sclerosis Using Treadmill Training Gait impairment is a major cause of ongoing disability in patients with multiple sclerosis (MS). New treadmills that provide body weight support and even robotic assistance to the lower limbs have recently been developed and are now commercially available. These treadmills allow the subject to execute the integrated process of walking in a task-specific manner that is repetitively reinforced in a normal pattern. Data from studies using these body-weight supported treadmills (BWSTT) in spinal cord injury and stroke patients suggest that intensive task-specific gait rehabilitative training may help to restore a normative gait pattern, improve overground walking and enhance quality of life in multiple sclerosis patients with neurological gait impairment. In this study, we propose a series of prospective longitudinal clinical studies to collect pilot data on the use of task-specific BWSTT +/- Lokomat on improving ambulation, motor function and quality of life for MS patients with mild to moderate gait difficulty. Pilot data will also be collected for the effect conventional rehabilitation has on ambulation and motor outcomes as well as how these outcomes change during usual care. Our clinical research goals are to capture the initial pilot data (mean changes and variances in ambulation, motor, fatigue and quality of life outcomes) to facilitate the design of a larger clinical trial to test efficacy if these preliminary data are promising. The planned studies will study the effect of two forms of task specific training (BWSTT alone and BWSTT combined with Lokomat) compared to conventional gait rehabilitative methods and usual care
Enhancing Walking in People With Incomplete Spinal Cord Injury: a Pilot Study Community-dwelling individuals with motor-incomplete spinal cord injury will be recruited. In total, 20 participants will be recruited and randomly assigned to one of 2 types of body-weight supported treadmill training (BWSTT) with the Lokomat, which differ only in the level of assistance that the Lokomat provides to the leg movements while walking. Therapy for both groups will take place 3 times/week for 12 weeks. During each session, participants will first complete a 10-minute warm-up period followed by 45 minutes of the assigned therapy. Rest breaks will be provided as needed, but participants should complete 45 minutes of walking per session.
This controlled study showed, at the end of a 6-week trial, that locomotor therapy with the use of RAGT combined with regular physiotherapy produced promising effects on functional and motor outcomes in patients after subacute stroke as compared with regular physiotherapy alone.
Robotic-assisted body-weight support treadmill training for spinal decompression sickness rehabilitation might be beneficial.
Pilot study of Lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke. Results suggest that Lokomat training may have advantages over manual-BWSTT following a modest intervention dose in chronic hemiparetic persons and further, that our training speeds produce similar gait improvements.
Children and adolescents with bilateral spastic cerebral palsy showed improvements in the functional tasks of standing and walking after a 3-week trial of robotic-assisted treadmill therapy. The severity of motor impairment affects the amount of the achieved improvement.
Robotic assisted treadmill therapy is a safe method to enable longer periods of gait therapy in children and adolescents with gait disorders.
Robot-aided training in rehabilitation Robot-aided therapy has enabled the functional training of the arm and the lower limbs in an effective, easy, and comfortable manner. Therefore, with this type of therapy, the patients can repeatedly undergo sufficient and accurate training for a prolonged period.
The improvements of motor function after a three-week trial of robotic-assisted treadmill therapy appear to be sustained after a mean period of six months.
This pilot study indicates that Lokomat therapy is a promising intervention for gait rehabilitation. Although there was no difference between groups in gain of functional scores, the Lokomat group showed an advantage of robotic training over conventional physiotherapy in improvement of gait abnormality and body tissue composition.
This proposal investigates the hypothesis that progressive aerobic exercise with Lokomat is feasible in motor incomplete SCI, theorizing that three months of training will improve cardiovascular fitness and gait functionality when compared to other physical therapy controls. We propose a two-phase study to examine the feasibility, reliability and utility of aerobic exercise metabolic testing and training during robotically assisted partial weight support treadmill walking in individuals with chronic motor incomplete spinal cord injury (CMISCI). During the first phase of the study, we will manipulate Lokomat training parameters of treadmill speed and percent of partial weight support to assess the effect of these changes on heart rate, perceived exertion, and oxygen consumption in untrained chronic motor incomplete spinal cord injured subjects. Subjects will be asked to maintain cardiovascular or muscular effort during testing and will be monitored in this regard by the force biofeedback system built into the Lokomat.
Lokomat Versus Strength Training in Chronic Incomplete Spinal Cord Injury Although task-specific training has been promoted during the last years to improve function, recent studies showed that after an incomplete spinal cord injury, strength, but not complex movement coordination, is affected. In this randomized cross-over trial we investigate the effectiveness of a task-specific 4 week Lokomat training with a 4 week (unspecific) lower extremity muscle strength training on walking-related and other outcomes.
Exercise-mediated (Lokomat) locomotor recovery and lower-limb neuroplasticity after stroke The ATLET Study: Can Subjects With Incomplete Spinal Cord Injury Learn to Walk? There are approximately 100 new cases of spinal cord injuries (SCI) each year in Norway. Most of the SCI occur after traumatic accidents among young people and adults during the time of their productive life. Loss of walking and standing ability restricts their independent mobility and autonomy and severely impacts their quality of life. The study has two arms: 1) manual locomotor training (Tromsø) and 2) robot assisted training (Oslo). Each study arm has 30 patients, randomized to receive standard care or intervention. The intervention group receives 60 days of intensive locomotor training over 6 months. Single-blind, before/after evaluation of effect will be performed at Sunnaas hospital using a standardized set of evaluation tools.
You can participate in this study if you have had a SCI at least 12 months ago at or above the 12th thoracic (T.12) level. In addition, you should be able to stand or walk for at least part of your daily activities, or alternatively, able to take steps with the help of a treadmill and part of your body weight supported. This study will take place at the Blusson Spinal Cord Centre (818 West 10th Ave). You will be randomly allocated (assigned by chance, like the flip of a coin) to one of 2 treatment groups. The 2 treatment groups differ only in the level of assistance that the Lokomat will provide to your leg movements while walking. You will not be informed of the group to which you have been assigned. Both treatment groups involve 45-minute treadmill training sessions, 3 times per week for 12 weeks (3 months) of training. You may take rest breaks during the sessions, but the total walking time must total 45 minutes. Given time for set-up and rest breaks, you can expect to spend about 1.5 hours in the laboratory for each visit. After the end of the 12 weeks of training, you will be asked to return to the laboratory for 2 follow-up tests, 1 month and 6 months later. The total amount of time for participating in this research will be 64-68hours (40 laboratory visits) over a 9-month period (including follow-up and medical visits).
Effectiveness of Robotic Assisted Gait Training in Children With Cerebral Palsy (PeLoGAIT) The purpose of the study is to investigate the effectiveness of robotic-assisted locomotor therapy on improvements of functional gait parameters in ambulatory children with cerebral palsy.
Effect of Robot-assisted Gait Training on Freezing of Gait in Parkinson's Disease Freezing of gait (FOG) is a common yet poorly understood motor symptom in persons with Parkinson's disease (PD). Previous studies have shown that bilateral uncoordinated gait and gait asymmetry are related to FOG, and that intensive treadmill training in PD patients can improve gait. However, no group has yet studied the effect of robot-assisted gait training (RAGT) on FOG. The primary aim of this study is to collect pilot data on the effect of robot-assisted gait training in reducing episodes of freezing in PD. Subjects with Parkinson's disease that experience freezing of gait will be recruited and enrolled following informed consent and screening for eligibility. Each of the 10 training session will last approximately one hour. Neurological evaluations, testing of gait parameters, and quality of life assessments will be conducted. Participants will also be asked to return for 1- and 3-month post-intervention assessments to see if the training has any lasting effects. Approximately 10-20 subjects will be enrolled, and the study will last up to 6 months. Robot-assisted gait training will be conducted with the Lokomat (a treadmill with supplemental robot-assistance for moving the hip and knee). We will monitor changes in freezing by conducting various assessments. There are approximately 1 million Americans with PD in the US. PD is a significant cause for reduced functional ability and quality of life, progressive disability. Patients with PD with FOG have indicated that this is one of their most disturbing symptoms, as there are no effective treatments. Therefore it is important that additional and alternative interventions for FOG be tested and developed.
Lokomat Training Effects On Multiple Sclerosis Gait Abnormalities Multiple sclerosis is a degenerative disease that affects more than 400,000 people in the US alone. MS is in fact the most common disabling neurological disorder in young adults. Symptoms of the disease can include problems with balance, walking, fatigue, weakness and vision. Over 85% of people with Multiple Sclerosis have problems walking. This can cause them to fall or have a constant fear of falling. To prevent falling, MS patients rely on equipment, such as walkers and canes. These costs can cause financial difficulties for MS patients and families. A significant problem that is only recently being studied is the relationship between falling and MS. Recent studies have shown that MS patients fall more often than those without MS, and also fall more than the elderly population. The consequent fear of falling is also an important problem, as those worried about falling will probably change their daily habits to lower their risk. This can mean keeping from certain physical and social activities or even staying indoors. Thus, falls and fear of falling can have negative medical, physical, psychological, and social consequences for the patient. Improving patients' walking may help reduce falls and the fear of falling. Treadmill training has been shown to improve walking in patients with MS and to lower their risk of falling. One way to train patients on a treadmill is with the use of robots that can help move their limbs in a more normal way. This kind of robot-assisted treadmill training may provide even greater benefits than treadmill training alone. The study is expected to last 6-7.5 months. One group of participants will receive weekly telephone calls and will be asked questions on other physical activities, falls, and activity limitations the patient had during the week. Participants assigned to robot-assisted treadmill training will receive twice weekly training session for 8 weeks, for a total of 16 sessions. Each session will last about 65 to 90 minutes. The goal of this study is to see if robot-assisted treadmill training will reduce falls and fear of falling in patients with MS. Robot-assisted treadmill training has been shown to be effective in reducing falls and fear of falling in Parkinson's disease patients. This type of training has not been tested in patients with Multiple Sclerosis. The proposed study will help to address this gap and also provide additional data on other possible improvements due to robot-assisted treadmill training including ambulation, social participation, fatigue, and balance.
Severe traumatic brain injury, especially after a high energy trauma, is characterised with focal lesions and diffuse axonal injury, which leads to the dysfunction in the cortico-spinal, cortico- cortical connections and reticular activation system. Formatio reticularis plays an important role in arousal. Tactile and proprioceptive stimulation with a view to improving level of consciousness in coma patients is popular in the western world despite insufficient evidence of its effectiveness. Affolter-Bobath-Coombes-concept is the most commonly used tool in the rehabilitation of brain damaged patients. This concept is based on the theory that tactile, proprioceptive and oral stimulation develops new connections in the brain and thereby stimulates consciousness and behaviour. Elliot et al shows improvement in level of consciousness due to postural changes from a lying position to a standing posture in 8 of 12 patients using Wessex Head Injury Matrix. Passive movements result in proprioceptive stimulation; the effect of which is close to that achieved by physiological voluntary activity. PET and fMRI studies show that passive movements activate several areas in the motor cortex. In order to increase afferent cortical input, passive gait training in the body weight support robotic gait orthosis could be used in patients with impaired consciousness, inability to cooperate and poor balance. This device gives the possibility to establish therapeutically correct upright body position and passive legs movement simultaneously. To our knowledge there are no studies, which illustrate the effects of passive gait training on cortical activity in patients with impaired consciousness due to severe traumatic brain injury. Our hypothesis is that passive gait training of this group of patients increases arousal, which can be shown in an increased EEG (electroencephalogram)-frequency and increased conductivity speed of the cognitive P300-component of ERP (Event Related Potentials). Comparison(s): EEG- and ERP-activity after a single training session in robotic gait orthosis in patients with severe traumatic brain injury, compared to EEG- and ERP-activity after a single training session in robotic gait orthosis in healthy persons.
Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis The primary aim of this study is to:
Hypothesis: Both trainings will result in improved walking performance, but the combination therapy will result in greater gains than ankle training alone.
Functional and Physiological Responses to Lokomat Therapy (Pilot Study) Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground. Loss of functional mobility not only impedes everyday life, but may also affect many systems and organs in the body. The investigators are interested in obtaining a wide variety of data in order to obtain a better understanding of changes that occur as a result of receiving Lokomat therapy. The investigators will be studying body composition, cardiac, pulmonary, endocrine, metabolic, and molecular changes after a 12-week clinical therapy program.
HyperMED Clinical Research/STROKE-2009-563247v2-Hornby.pdf Locomotor training improves daily stepping activity and gait efficiency in individuals post stroke who have reached a 'plateau' in recovery Prof George Hornby
Pilot study of Lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke Results suggest that Lokomat training may have advantages over manual-BWSTT following a modest intervention dose in chronic hemiparetic persons and further, that our training speeds produce similar gait improvements.
This proposal investigates the hypothesis that progressive aerobic exercise with Lokomat is feasible in people with motor incomplete spinal cord injury, and three months of training will improve cardiovascular fitness and gait functionality when compared to physical therapy...
Effect of Robot-assisted Gait Training on Freezing of Gait in Parkinson's Disease Freezing of gait (FOG) is a common yet poorly understood motor symptom in persons with Parkinson's disease (PD). Previous studies have shown that bilateral uncoordinated gait and gait asymmetry are related to FOG, and that intensive treadmill training in PD patients can improve gait. However, no group has yet studied the effect of robot-assisted gait training (RAGT) on FOG. The primary aim of...
Feasibility and Practice Characteristics of FNS and Gait Robot Conventional therapies do not restore normal gait for many stroke survivors. The long-term goal of this work is to restore volitional lower limb motor control and gait following stroke. In our prior work, we demonstrated that it was feasible to provide a clinically operated, combined treatment of body weight supported treadmill training alone (BWSTT) + functional neuromuscular stimulation (FNS) using intramuscular (IM) electrodes (FNS-IM). Specific Aims and Hypothesis The purpose or Specific Aim of the study is to test the feasibility and gait training potential of combining the Lokomat and FNS-IM for stroke survivors. Given the feasibility of our clinically operated combination of BWSTT + FNS-IM, we propose to test the feasibility of the combination of Lokomat + FNS-IM. Hypothesis I. It is feasible to utilize a clinically operated combination of Lokomat + functional neuromuscular stimulation (FNS) with intramuscular (IM) electrodes (FNS-IM). Treatment Procedures. The subjects will be treated for three months, four sessions/week (for a total of 48 treatment visits). A given session will be 1½ hrs, with the time divided into thirds as follows: 1) ½ hr coordination exercise; 2) ½ hr over ground gait training; and 3) ½ hr Lokomat gait training. FNS-IM will be used in all three aspects of the protocol, unless the subject is capable of volitionally executing a given movement or gait component. Population. The subjects will be chronic stroke survivors (>6 months after the stroke).
HyperMED/Lokomat - Australian Experience HyperMED NeuroRecovery.pdf
Gait Training for Persons With Stroke - Full Text View - ClinicalTrials.gov ... is to investigate the effects of an automatic gait trainer (Lokomat) handled by physical therapists compared with categorized gait training ... used to evaluate study effects. Hypotheses: 1) The Lokomat improves stroke patients gait speed distance and symmetry more than categorized gait training. ... http://www.clinicaltrials.gov/ct2/show/NCT00612300?cond=%22Cerebral+Infarction%22
Healogica: NCT00883142 - Functional and Physiological Responses to Lokomat Therapy Trial Summary Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground. Loss of functional mobility not only impedes everyday life, but may also affect many systems and organs in the body. The investigators are interested in obtaining a wide variety of data in order to obtain a better understanding of changes that occur as a result of receiving Lokomat therapy. The investigators will be studying body composition, cardiac, pulmonary, endocrine, metabolic, and molecular changes after a 12-week clinical therapy program. Any patient who is already eligible for Lokomat therapy is a candidate for this .... ClinicalTrials.gov processed this record on April 16, 2009 https://www.healogica.com/trials/multiple.../NCT00883142/ ... To compare the efficacy of robotic-assisted gait training with the Lokomat to conventional gait training in individuals with subacute stroke. ... All participants received twenty-four 1-hour sessions of either Lokomat or conventional gait training. Outcome measures were evaluated prior ... http://nnr.sagepub.com/cgi/content/abstract/23/1/5
Lokomat Treadmill Training Effects on MS Gait - Full Text View - ClinicalTrials.gov ... possible benefits of gait-specific training using body-weight supported Lokomat assisted treadmill training in people with Multiple Sclerosis. ... (Outcomes Assessor) Dose Comparison Parallel Assignment Safety Study Official Title: Lokomat Treadmill Training Effects on MS Gait ... http://www.clinicaltrials.gov/ct2/show/NCT00835835?state1=NA%3aUS%3aCT
... leg muscle electromyography activity evoked by mechanically assisted locomotion (Lokomat) in biceps femoris rectus femoris tibialis anterior and gastrocenmius medialis. ... http://brain.oxfordjournals.org/cgi/content/short/132/8/2196?ck=nck
Kinematic trajectories while walking within the Lokomat robotic gait-orthosis. ... Background One of the most popular robot assisted rehabilitation devices used is the Lokomat. Unfortunately not much is known about the behaviors exhibited ... was to evaluate the kinematic patterns of individuals walking inside the Lokomat compared to those demonstrated on a treadmill. ... pubmed.com Dec 1, 2008
... This proposal investigates the hypothesis that progressive aerobic exercise with Lokomat is feasible in people with motor incomplete spinal cord injury ... robotically assisted partial weight support treadmill training devices such as Lokomat in chronic incomplete spinal cord injured subjects. ... http://www.clinicaltrials.gov/ct2/show/NCT00385918?cond=%22Nervous+System+Diseases%22+AND+%22Paraplegia%22&rank=5
... OBJECTIVE: To compare the efficacy of robotic-assisted gait training with the Lokomat to conventional gait training in individuals with subacute stroke. ... All participants received twenty-four 1-hour sessions of either Lokomat or conventional gait training. Outcome measures were evaluated prior ... pubmed.com Jan 1, 2009
Gait Training for Persons With Stroke - Tabular View - ClinicalTrials.gov ... is to investigate the effects of an automatic gait trainer (Lokomat) handled by physical therapists compared with categorized gait training ... used to evaluate study effects. Hypotheses: 1) The Lokomat improves stroke patients gait speed distance and symmetry more than categorized gait training. ... http://www.clinicaltrials.gov/ct2/show/record?intr=%22Physical+Therapy%22&rank=27
... Related Studies Functional and Physiological Responses to Lokomat Therapy (Pilot Study) This study is currently recruiting participants. ... http://www.clinicaltrials.gov/ct2/show/NCT00883142?cond=%22Cerebral+Infarction%22
... The Lokomat is a motor driven exoskeleton device that employs a body weight support suspension system and treadmill. Attached to the lower limbs the Lokomat moves the subject's legs over a treadmill through position controlled ... http://www.clinicaltrials.gov/ct2/show/NCT00872053?recr=Open&intr=%22robotic+device%22
... Robot-assisted gait training will be conducted with the Lokomat (a treadmill with supplemental robot-assistance for moving the hip ... Attached to the lower limbs the Lokomat moves the subject's legs through position controlled trajectories that mimic ... http://www.clinicaltrials.gov/ct2/show/NCT00819949?recr=Open&cond=%22Nervous+System+Diseases%22
Neurorehabilitation and
Neural Repair
... potential efficacy of using an electromechanical-driven gait orthosis (Lokomat) for treadmill training. Methods. ... groups ABA or BAB (A = 3 weeks of Lokomat training B = 3 weeks of conventional physical therapy) ... http://nnr.sagepub.com/cgi/reprint/21/4/307.pdf
... Other: Lokomat training Study Arms / Comparison Groups Publications * * Includes publications given by the data provider as well ... http://www.clinicaltrials.gov/ct2/show/NCT00887848?term=cerebral&recr=Open&cond=%22Nervous+System+Diseases%22
... according to a study that tested the effectiveness of the Lokomat an FDA-approved robotic gait orthotic device that was developed ... robotic-assisted LT were provided continuous symmetrical stepping assistance using the Lokomat. With body-weight supports the subjects were attached ... http://www.biomech.com/full_article/?ArticleID=1101&month=09&year=2008
... gait training strategy using a robotic gait trainer (the Lokomat) on functional ambulation in people with SCI. ... body-weight supported treadmill training (BWSTT) with the Lokomat which differ only in the level of assistance ... http://www.clinicaltrials.gov/ct2/show/NCT00610974?cond=%22Nervous+System+Diseases%22
... Intervention † Device: Anklebot Device: Lokomat Study Arms / Comparison Groups Experimental: Focused Ankle Training Experimental: Combination Therapy Publications ... breakdown in areas in contact with the body harness or Lokomat apparatus. Chronic and ongoing alcohol or drug abuse. ... http://www.clinicaltrials.gov/ct2/show/NCT00872053?intr=%22robotic+device%22&map=NA%3aUS
... that was combined with a robot-driven gait orthosis the Lokomat which physiologically exercises the legs of a patient on a moving treadmill. Subjects performed different Lokomat conditions after measurement of the baseline i.e. standing ...
Gait Training for Persons With Stroke - Related Studies - ClinicalTrials.gov ... Vascular Diseases Interventions listed in this trial Lokomat - Physical therapy Physical therapy - Lokomat Sponsors listed in this trial University of Aarhus Back to top of Main Content . ... http://www.clinicaltrials.gov/ct2/show/related?intr=%22Physical+Therapy%22&rank=27
... To facilitate treadmill training of paraparetic patients a robot-driven gait orthosis (Lokomat) was developed. We investigated the effects ... Results— After 4 weeks of therapy the walking ability of the Lokomat group and the control group expressed as the functional ambulation ... http://stroke.ahajournals.org/cgi/content/full/38/2/349?ck=nck
... gait training strategy using a robotic gait trainer (the Lokomat) on functional ambulation in people with SCI. ... body-weight supported treadmill training (BWSTT) with the Lokomat which differ only in the level of assistance ... http://www.clinicaltrials.gov/ct2/show?intr=%22Treadmill+Training%22&rank=4 www.clinicaltrials.gov Jun 23, 2008
... groups ABA or BAB (A = 3 weeks of Lokomat training B = 3 weeks of conventional physical therapy) ... Scale and Ashworth Scale demonstrated significantly more improvement during the Lokomat training phase than during the conventional physical therapy phase ... http://nnr.sagepub.com/cgi/content/abstract/1545968307300697v1?ck=nck nr.sagepub.com May 2, 2007
... Trauma Nervous System Wounds and Injuries Interventions listed in this trial Lokomat Training Home stretching protocol Sponsors listed in this trial ... http://www.clinicaltrials.gov/ct2/show/related/NCT00385918?intr=%22Treadmill+Training%22&rank=16 www.clinicaltrials.gov Mar 17, 2009
... In the driven gait orthosis (DGO) Lokomat an estimation of the patient's activity level was based ... pubmed.com Feb 1, 2009
... healthy participants after active and passive robotic gait training in a driven gait orthosis (DGO) the Lokomat. ... http://nnr.sagepub.com/cgi/content/abstract/23/2/143
... METHODS: Robotic-assisted body-weight support treadmill training was administrated using the Lokomat. Primary outcomes were American Spinal Cord Association scale Spinal ... Brown-Sequard syndrome. After 3 months of rehabilitation including 18 Lokomat sessions American Spinal Cord Association score improved from C ...
Virtual gait training for children with cerebral palsy using the Lokomat gait orthosis. ... 204-9 The Lokomat gait orthosis was developed in the Spinal Cord Injury Center at the University Hospital Balgrist Zurich and provides automatic ... (CP). Each patient undergoes a task-oriented Lokomat rehabilitation training program via a virtual reality setup. ...
... movement of the paretic leg and a robotic device called the Lokomat that moves your legs over a treadmill with body weight support. ... externally-driven modes of BWSTT. Externally-driven BWSTT (Lokomat) produces a more controlled consistent and mechanically appropriate locomotor ... http://www.clinicaltrials.gov/ct2/show?term=recovery&cond=%22Cerebrovascular+Accident%22&rank=23
... prescribing near normal physiological gait patterns with the use of the Lokomat robotic gait-orthosis could help ameliorate asymmetries in gait specifically ... patterns common to stroke gait. CONCLUSION: Despite the Lokomat guiding stroke subjects through physiologically symmetric kinematic gait patterns abnormal ...
... potential efficacy of using an electromechanical-driven gait orthosis (Lokomat) for treadmill training. METHODS: Sixteen stroke patients ... groups ABA or BAB (A = 3 weeks of Lokomat training B = 3 weeks of conventional physical therapy) ...
Cortical and spinal excitability changes after robotic gait training in healthy participants. ... training in a driven gait orthosis (DGO) the Lokomat. METHODS: Thirteen healthy participants took part in 2 experiments. ...
... Body weight supported treadmill training (BWSTT) with or without robotic assistance (Lokomat) was tested using a randomized crossover design in 13 ... http://nnr.sagepub.com/cgi/content/abstract/22/6/661?rss=1
Limb alignment and kinematics inside a Lokomat robotic orthosis. ... systems has become commonplace world-wide. In particular the Lokomat robotic orthosis (Hocoma AG Volketswil Switzerland) ... Here we report differences in kinematic trajectories between walking in the Lokomat and walking on a treadmill as well as the relative ...
... To facilitate treadmill training of paraparetic patients a robot-driven gait orthosis (Lokomat) was developed. We investigated the effects ... Results--After 4 weeks of therapy the walking ability of the Lokomat group and the control group expressed as the functional ambulation ... http://stroke.ahajournals.org/cgi/content/abstract/strokeaha;01.STR.0000254607.48765.cbv1
... attached to each lower extremity or by a velocity-dependent resistance applied by the Lokomat robotic gait orthosis. ... http://nnr.sagepub.com/cgi/content/abstract/22/5/438?rss=1
... stimulation using intramuscular electrodes (FES-IM) and the Lokomat robotic gait orthosis. A system of hardware and software ... The bench tests showed that automatic synchronization of FES-IM to the Lokomat gait cycle was feasible and reliable. ...
... Gait training: Gait robot (Lokomat® Hocoma Switzerland) is adjusted to the patient/healthy volunteer individually with chest ... Gait training: Gait robot (Lokomat® Hocoma Switzerland) is adjusted to the patient/healthy volunteer individually with chest ... http://www.clinicaltrials.gov/ct2/show?cond=%22Nervous+System+Diseases%22+AND+%22Craniocerebral+Trauma%22&rank=13
An accelerometry-based comparison of 2 robotic assistive devices for treadmill training of gait. ... OBJECTIVE: Two commercial robotic devices the Gait Trainer (GT) and the Lokomat (LOKO) assist task-oriented practice of walking. ...
... Two commercial robotic devices the Gait Trainer (GT) and the Lokomat (LOKO) assist task-oriented practice of walking. ... http://nnr.sagepub.com/cgi/content/abstract/22/4/348?ck=nck
... Two studies investigated the robotic-assisted device "Lokomat" as one of the experimental interventions and all four ... http://injuryprevention.bmj.com/cgi/content/full/14/3/209
... For example the application of locomotor assistance using 1 commercial device the Lokomat (Hocoma Medial Engineering Inc Zurich) ... Subjects randomized to robotic-assisted LT were provided continuous symmetrical stepping assistance using the Lokomat. The design and control of this device have been described previously. ... http://stroke.ahajournals.org/cgi/content/full/39/6/1786
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://stroke.ahajournals.org/cgi/content/short/39/6/1786?ck=nck
... (SCI). Hip goniometric information from the Lokomat system defined midstance and midswing points within the gait cycle. ...
Standardized voluntary force measurement in a lower extremity rehabilitation robot. ... was implemented in the driven gait orthosis (DGO) Lokomat. To evaluate the capabilities of this new measurement method ...
Treadmill training with partial body weight support after stroke: a review. ... effective as walking on the floor. Gait machines as the Lokomat or the Gait Trainer GTI intend to relieve the strenuous ...
... The passive stepping was produced by a robotic gait trainer Lokomat. The cutaneous reflexes following electric stimulation to the distal
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://jap.physiology.org/cgi/content/abstract/01380.2006v1?ck=nck
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://nnr.sagepub.com/cgi/content/abstract/22/1/22?ck=nck
... The second group will receive walking therapy using a Lokomat which is a special treadmill that works in conjunction ... Some of the subject’s body-weight will be supported using a harness. During Lokomat training sessions subjects will receive feedback of their walking performance ... http://www.clinicaltrials.gov/ct2/show?intr=%22Physical+Therapy%22&state1=NA%3aUS%3aDC&rank=2
ClinicalTrials.gov - Information on Clinical Trials and Human Research Studies ... The second group will receive walking therapy using a Lokomat which is a special treadmill that works in conjunction ... Some of the subject’s body-weight will be supported using a harness. During Lokomat training sessions subjects will receive feedback of their walking performance ... http://www.clinicaltrials.gov/ct2/show/NCT00075283?term=rehabilitation&cond=%22Cerebrovascular+Accident%22&rank=50
Quantum Sufficit - July 1, 2004 - American Family Physician ... A robot named Lokomat is helping patients with spinal cord injuries learn to walk again according to a press release ... brain to signal the body to step. After using Lokomat for a month a 50-year-old patient paralyzed ... http://www.aafp.org/afp/20040715/quantum.html
... The second group will receive walking therapy using a Lokomat which is a special treadmill that works in conjunction ... Some of the subject’s body-weight will be supported using a harness. During Lokomat training sessions subjects will receive feedback of their walking performance ... http://www.clinicaltrials.gov/ct2/show?term=rehabilitation&recr=Open&cond=%22Cerebrovascular+Accident%22&rank=42
Gait rehabilitation machines based on programmable footplates. ... machines either consisting of a powered exoskeleton and a treadmill (Lokomat AutoAmbulator) or an electromechanical solution with the harness secured ...
Neurorehabilitation and
Neural Repair
... that fMRI changes in cortical activation for voluntary plantarflexion following Lokomat training may not be what would be observed during walking. ... related to changes in their locomotor status and gait speed following Lokomat body weight–supported training. We would reason that if spontaneous ... http://nnr.sagepub.com/cgi/reprint/20/1/233.pdf
Alterations in muscle activation patterns during robotic-assisted walking. ... Activity in the quadriceps and hamstrings was significantly higher during the swing phase of Lokomat walking than treadmill walking while activity in the ankle flexor ... was reduced throughout most of the gait cycle in the Lokomat. CONCLUSIONS: Walking within a robotic orthosis that limits ...
... Half received assistance from a therapist as needed and half had constant guidance from a robotic orthosis called Lokomat. ... http://www.medpagetoday.com/Cardiology/Strokes/tb/9394
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://nnr.sagepub.com/cgi/content/abstract/21/1/25
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://stroke.ahajournals.org/cgi/content/short/01.STR.0000181076.91805.89v1
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://jap.physiology.org/cgi/content/abstract/97/4/1299?ck=nck
Upper and lower extremity robotic devices for rehabilitation and for studying motor control. ... compared with treadmill training with body weight support. The Lokomat consisting of a treadmill and a powered exoskeleton lessened
... For assisted walking the driven gait orthosis (DGO) ‘Lokomat’ (Hocoma AG Zurich) mounted on a treadmill was used. ... http://brain.oxfordjournals.org/cgi/content/full/127/10/2221?ck=nck
... standing and 40 minutes of walking with stepping assistance from a Lokomat-driven gait orthosis. RESULTS: A resting VO2 equal
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/abstract/01.STR.0000035734.61539.F6v1
... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://jap.physiology.org/cgi/content/abstract/96/5/1954?ck=nck
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://jap.physiology.org/cgi/content/abstract/94/5/1766
... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://brain.oxfordjournals.org/cgi/content/short/125/12/2626
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://www.neurology.org/cgi/content/abstract/neurology;66/4/484
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/short/29/6/1122?rss=1&ssource=mfc
... During walking with a driven gait orthosis (DGO) ‘Lokomat’ (Hocoma AG Zurich) on a treadmill ...
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/short/26/6/976
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://ageing.oxfordjournals.org/cgi/content/abstract/12/2/166?ck=nck
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://stroke.ahajournals.org/cgi/content/short/23/8/1084
... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/short/28/5/988
... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/abstract/strokeaha;28/2/326
... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://physrev.physiology.org/cgi/content/abstract/80/1/83?ck=nck
Evidence Based ... This Article Services Citing Articles Google Scholar PubMed Social Bookmarking Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Joseph Hidler PhD Department of Biomedical Engineering Catholic University Washington DC; ... To compare the efficacy of robotic-assisted gait training with the Lokomat to conventional gait training in individuals with subacute stroke. ... http://nnr.sagepub.com/cgi/content/abstract/23/1/5
Patient-Driven Cooperative Gait Training with the Rehabilitation ...www.springerlink.com © Springer-Verlag Berlin Heidelberg 2009. Patient-Driven Cooperative Gait Training with the ... treadmill speed during Lokomat training [6] provides free ... Lokomat impedance controller by a set point generation ...
“The Use of the Lokomat System in Clinical Research” February 12, 2009. “The Use of the Lokomat System in Clinical Research”. Keith Tansey, MD, PhD. Director, Spinal Cord Injury Research ... www.inrs2009.com/.../Tansey_TheUseofTheLokomatSystemInClinicalResearch_INRS2009.pdf -
... OBJECTIVE: To compare the efficacy of robotic-assisted gait training with the Lokomat to conventional gait training in individuals with subacute stroke. ... All participants received twenty-four 1-hour sessions of either Lokomat or conventional gait training. Outcome measures were evaluated prior ... pubmed.com Jan 1, 2009
Neurorehabilitation and Neural Repair ... Neurorehabilitation and Neural Repair http://nnr.sagepub.com Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Andreas Mayr Markus Kofler Ellen Quirbach Heinz Matzak Katrin Fröhlich and Leopold Saltuari ... potential efficacy of using an electromechanical-driven gait orthosis (Lokomat) for treadmill training. Methods. ... http://nnr.sagepub.com/cgi/reprint/21/4/307.pdf
... To facilitate treadmill training of paraparetic patients a robot-driven gait orthosis (Lokomat) was developed. We investigated the effects ... Results— After 4 weeks of therapy the walking ability of the Lokomat group and the control group expressed as the functional ambulation ... http://stroke.ahajournals.org/cgi/content/full/38/2/349?ck=nck
... This Article Services Citing Articles Google Scholar PubMed Social Bookmarking Article Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Andreas Mayr MS Marcus Kofler MD* Ellen Quirbach PT Heinz Matzak MD Katrin Fröhlich MD Leopold Saltuari MD ... groups ABA or BAB (A = 3 weeks of Lokomat training B = 3 weeks of conventional physical therapy) ... http://nnr.sagepub.com/cgi/content/abstract/1545968307300697v1?ck=nck
... potential efficacy of using an electromechanical-driven gait orthosis (Lokomat) for treadmill training. METHODS: Sixteen stroke patients ... groups ABA or BAB (A = 3 weeks of Lokomat training B = 3 weeks of conventional physical therapy) ... pubmed.com Jul 1, 2007
... To facilitate treadmill training of paraparetic patients a robot-driven gait orthosis (Lokomat) was developed. We investigated the effects ... Results--After 4 weeks of therapy the walking ability of the Lokomat group and the control group expressed as the functional ambulation ... http://stroke.ahajournals.org/cgi/content/abstract/strokeaha;01.STR.0000254607.48765.cbv1
... For example the application of locomotor assistance using 1 commercial device the Lokomat (Hocoma Medial Engineering Inc Zurich) ... Subjects randomized to robotic-assisted LT were provided continuous symmetrical stepping assistance using the Lokomat. The design and control of this device have been described previously. ... http://stroke.ahajournals.org/cgi/content/full/39/6/1786
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://stroke.ahajournals.org/cgi/content/short/39/6/1786?ck=nck
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://nnr.sagepub.com/cgi/content/abstract/21/1/25
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... http://stroke.ahajournals.org/cgi/content/short/01.STR.0000181076.91805.89v1
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/abstract/01.STR.0000035734.61539.F6v1
... Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke Neurorehabil Neural Repair January 1 2009; ... Prospective Blinded Randomized Crossover Study of Gait Rehabilitation in Stroke Patients Using the Lokomat Gait Orthosis Neurorehabil Neural Repair July 1 2007; ... http://stroke.ahajournals.org/cgi/content/abstract/strokeaha;33/2/553
... according to a study that tested the effectiveness of the Lokomat an FDA-approved robotic gait orthotic device that was developed ... robotic-assisted LT were provided continuous symmetrical stepping assistance using the Lokomat. With body-weight supports the subjects were attached ... http://www.biomech.com/full_article/?ArticleID=1101&month=09&year=2008
Quantum Sufficit - July 1, 2004 - American Family Physician ... A robot named Lokomat is helping patients with spinal cord injuries learn to walk again according to a press release ... brain to signal the body to step. After using Lokomat for a month a 50-year-old patient paralyzed ... http://www.aafp.org/afp/20040715/quantum.html ... Half received assistance from a therapist as needed and half had constant guidance from a robotic orthosis called Lokomat. ... http://www.medpagetoday.com/Cardiology/Strokes/tb/9394
Effects of Locomotion Training With Assistance of a Robot-Driven Gait Orthosis in Hemiparetic Patients After Stroke. A Randomized Controlled Pilot Study. Husemann B, Müller F, Krewer C, Heller S, Koenig E. American Stroke Association; Stroke; 2007;38:349-354.
Biofeedback for robotic gait rehabilitation Luenenburger L, Colombo G, Riener R. Journal of NeuroEngineering and Rehabilitation; 4:1, 2007.
Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis. Mayr A, Kofler M, Quirbach E, Matzak H, Fröhlich K, Saltuari L. Neurorehabil Neural Repair. 2007 Jul-Aug;21(4):307-14.
Robot-assisted gait training for children with central motor disorders Meyer-Heim A, Reiffer C, Borggraefe I. praxis ergotherapie, Heft 1/2007, verlag modernes lernen, D-44287 Dortmund, Germany
The influence of different Lokomat walking conditions on the energy expenditure of hemiparetic patients and healthy subjects. Krewer C, Müller F, Husemann B, Heller S, Quintern J, Koenig E. Gait Posture. 2006 in press (doi:10.1016/j.gaitpost.2006.10.003).
Human-centered robotics applied to gait training and assessment. Riener R, Luenenburger L, Colombo G. J Rehabil Res Dev. 2006 Sep-Oct; 43(5):679-94.
Robotic-assisted, body-weight-supported treadmill training in individuals following motor incomplete spinal cord injury. Hornby TG, Zemon DH, Campbell D. Physical Therapy 85(1):52-66, 2005.
Therapeutic Effects of Robotic-Assisted Locomotor Training on Neuromuscular Properties. Mirbagheri MM, Tsao C, Pelosin E, Rymer WZ. Proceedings of the IEEE 9th International Conference on Rehabilitation Robotics (ICORR), Chicago USA, 561-564, 2005.
Changes in supraspinal activation patterns following robotic locomotor therapy in motor-incomplete spinal cord injury. Winchester P, McColl R, Querry R, Foreman N, Mosby J, Tansey K, Williamson J. Neurorehabil Neural Repair 19: 313-24, 2005.
Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: a multicenter trial. Wirz M, Zemon DH, Rupp R, Scheel A, Colombo G, Dietz V, Hornby TG. Arch Phys Med Rehabil 86:672-80, 2005.
Driven gait orthosis for improvement of locomotor training in paraplegic patients. Colombo G, Wirz M, Dietz V. Spinal Cord 39:252-255, 2001.
|
